Which is more sedating

It is less likely to cause marked residual daytime sedation than benzodiazepines. Zolpidem main drawback is that it is habit-forming. The research provides strong evidence that zolpidem abuse and dependence potential is much lower than that of benzodiazepines. You may have difficulty sleeping (rebound insomnia) after you stop taking the drug. Zolpidem is known to cause withdrawal symptoms in people who quickly stop the medicine after taking it regularly for a long time. Zolpidem has a tendency to gradually lose its efficacy when taken nightly for longer than two weeks. Zolpidem can cause bizarre behavior (parasomnia) that goes beyond traditional sleep-walking, such as memory loss, sleep-cooking, night time snacking, making phone calls while asleep. Modern hypnotics zolpidem, zaleplon, eszopiclone, and ramelteon are found to increase the risk of developing depression. Ambien user reviews on Ambien (Zolpidem) - reviews, ratings, comments by patients on Drug Lib Ambien (Zolpidem) reviews on View Points Zaleplon (Sonata®) is the weakest of the sedative pills with ultra-short half-life of about 1 hour.

However, zolpidem may cause grogginess if you sleep less than eight hours. Zolpidem does not accumulate in the body during repeated use. The drug may be taken at bedtime or later as long as the patient can sleep for at least 4 hours.

It is specifically indicated for insomnia characterized by difficulty in falling asleep.

This means that first-generation antihistamines are more likely to cause side effects such as sedation, dry mouth, dizziness, low blood pressure, and a rapid heart-beat.

They are also more likely than second-generation antihistamines to impair a person’s ability to drive or operate machinery.

Controlled-release version Ambien CR may theoretically be more effective for sleep maintenance than regular Ambien, but might also lead to more pronounced next day hangover. Sonata has more rapid onset of hypnotic effect than zolpidem (Ambien). Zaleplon can be taken during the night if you have problems staying asleep. Zaleplon is metabolized much more quickly than other sleep aids, so is far less likely to leave you feeling sleepy in the morning. Another potential benefit is minimal rebound insomnia after discontinuation.

If you have less than six hours to sleep, it is much more likely that you will still feel sedated or lethargic when you get up. Zaleplon may not work well if it is taken after heavy or high fat foods. There is a chance that you may experience a certain type of memory loss (amnesia). Sonata (Zaleplon) reviews, ratings, comments by patients on Drug Lib Eszopiclone (Lunesta®) is a short acting non-benzodiazepine sedative hypnotic and belongs to the class of drugs known as cyclopyrrolones.

They act on histamine-1 receptors in the periphery and are unlikely to penetrate the brain, so are less likely to cause side effects or interact with drugs.

Most second-generation antihistamines do not cause drowsiness, although some (such as cetirizine and fexofenadine), may be more likely to do so at higher dosages.Sedating antihistamines have the ability to cross the blood-brain barrier, the ability to bind to non-histamine receptors and have less selectivity for peripheral or central H1-receptors.The most common adverse effects with sedating antihistamines are sedation, dizziness and incoordination.Symptomatic measures, such as increasing fluids, making sure children get enough rest and reducing the spread of the virus (including regular hand washing) should be practiced.For children requiring antihistamines for allergies, a non-sedating antihistamine such as loratadine or cetirizine is preferred.They act on histamine receptors in the brain and spinal cord and in the rest of the body (called the periphery).