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In addition, it can impair the immune system, scientists from the German Cancer Research Center (DKFZ), the University Hospitals in Mannheim and Heidelberg, and the German Cancer Consortium now report.

It thus blocks the body's immune response in the battle against the mutant molecule and also impedes immunotherapy against brain cancer.

Among them are 14 genes that have not yet been associated with breast cancer.

This finding opens new insights into cancer development and progression and it also suggests that rethinking antitumor immunotherapy is required.

Most diabetes medications do not attack the cause of the disease.

Microproteins essential for cancer growth Breast cancer is one of the leading causes of death in women worldwide.

In order to develop new therapies, it is necessary to understand exactly how breast cancer cells function.

In a large international network, in which numerous DKFZ researchers were also involved, scientists have now combined genome-wide association studies with an estimation of the gene activity.

They identified 48 genes whose activity is associated with breast cancer risk.

The results of the recently published study should help to better tailor breast cancer follow-up to the patients' complaints. An international comparison Whether or not a medical treatment is added to the catalogue of services covered by a national health care scheme, in many jurisdictions largely depends on the economic assessment of its cost benefit ratio.

The so-called "value of a statistical life year" (VSLY) is an important point of reference for this assessment.

Malaria is one of the most inflicting infectious diseases worldwide.

Scientists from the German Cancer Research Center (DKFZ) in Heidelberg, Germany, and from The Hospital for Sick Children (Sick Kids) in Toronto, Canada, have studied how the human immune system combats malaria infections.

This opens up new possibilities for developing therapies against age-related diseases.